diff --git a/Ghidra/Features/PyGhidra/src/main/py/README.md b/Ghidra/Features/PyGhidra/src/main/py/README.md
index b68c86131d..4550be5b4b 100644
--- a/Ghidra/Features/PyGhidra/src/main/py/README.md
+++ b/Ghidra/Features/PyGhidra/src/main/py/README.md
@@ -325,6 +325,11 @@ import pdb   # imports Python's pdb
 import pdb_  # imports Ghidra's pdb
 ```
 ## Change History
+__2.2.1:__
+* PyGhidra now launches with the current working directory removed from `sys.path` to prevent
+  the potential for importing invalid modules from random `ghidra/` or `java/` directories that may 
+  exist in the user's current working directory.
+
 __2.2.0:__
 * [`pyghidra.open_program()`](#pyghidraopen_program) and 
   [`pyghidra.run_script()`](#pyghidrarun_script) now accept a `nested_project_location` parameter
diff --git a/Ghidra/Features/PyGhidra/src/main/py/src/pyghidra/__init__.py b/Ghidra/Features/PyGhidra/src/main/py/src/pyghidra/__init__.py
index c404603f10..acff535673 100644
--- a/Ghidra/Features/PyGhidra/src/main/py/src/pyghidra/__init__.py
+++ b/Ghidra/Features/PyGhidra/src/main/py/src/pyghidra/__init__.py
@@ -13,7 +13,7 @@
 # See the License for the specific language governing permissions and
 # limitations under the License.
 ##
-__version__ = "2.2.0"
+__version__ = "2.2.1"
 
 # stub for documentation and typing
 # this is mostly to hide the function parameter
diff --git a/Ghidra/Features/PyGhidra/src/main/py/src/pyghidra/launcher.py b/Ghidra/Features/PyGhidra/src/main/py/src/pyghidra/launcher.py
index a8864d65f1..1b8ed13bfc 100644
--- a/Ghidra/Features/PyGhidra/src/main/py/src/pyghidra/launcher.py
+++ b/Ghidra/Features/PyGhidra/src/main/py/src/pyghidra/launcher.py
@@ -429,6 +429,10 @@ class PyGhidraLauncher:
             **jpype_kwargs
         )
 
+        # Remove CWD from sys.path so we don't try to import from unintentional directories
+        # (i.e, an unrelated "ghidra" directory the user may have created)
+        sys.path.remove(os.getcwd())
+
         # Install hooks into python importlib
         sys.meta_path.append(_PyGhidraImportLoader())
         sys.meta_path.append(_GhidraBundleFinder())